MFAP1,微原纤维胶原相关蛋白1抗体

产品编号HZ-7810R
英文名称MFAP1
中文名称微原纤维胶原相关蛋白1抗体
别 名MFAP1 is an extracellular protein associated with elastic fiber microfibrils.
说 明 书0.1ml 0.2ml
研究领域细胞生物 信号转导 细胞周期蛋白 细胞骨架 细胞外基质
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Pig, Cow,
MFAP1,微原纤维胶原相关蛋白1抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量52kDa
细胞定位细胞外基质 分泌型蛋白
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human MFAP1
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
MFAP1,微原纤维胶原相关蛋白1抗体PubMedPubMed
产品介绍background:
Microfibrils are an important component of the extracellular matrix of many tissues and can either associate with or without elastin. Several microfibril associated proteins (MFAPs) have been cloned, including MFAP1, MFAP3 and MFAP4. The MFAP1 and MFAP3 genes are localized near the fibrillin genes FBN1 and FBN2, respectively. Mutations in FBN1 are linked to Marfan syndrome. Mutations in FBN2 have been linked to congenital contractural arachnodactyly. This suggests roles for MFAP1 and MFAP3 in heritable diseases affecting microfibrils. Deletion of MFAP4 was found in 30 of 31 patients with Smith-Magenis syndrome (SMS), a clinically recognizable multiple congenital anomaly/mental retardation syndrome.

Function:
Component of the elastin-associated microfibrils.

Subcellular Location:
Secreted, extracellular space, extracellular matrix.

Similarity:
Belongs to the MFAP1 family.

Database links:
Entrez Gene: 510905 Cow
Entrez Gene: 4236 Human
Entrez Gene: 100034361 Mouse
Entrez Gene: 67532 Mouse
Omim: 600215 Human
SwissProt: 5EA98 Cow
SwissProt: P55081 Human
SwissProt: Q9CQU1 Mouse
Unigene: 61418 Human
Unigene: 270393 Mouse
Unigene: 440764 Mouse

MFAP1,微原纤维胶原相关蛋白1抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.